Manny Pacquiao's trainer Freddie Roach said he would order the Filipino boxing great to retire if he suffers a bad loss in next week's comeback fight against Brandon Rios.
The flamboyant Roach backed Pacquiao for a fifth or sixth-round knockout of the American in their November 24 World Boxing Organisation welterweight title bout in Macau.
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But if the fight does not go according to plan, he said he would have no hesitation in telling Pacquiao to quit the sport after what would be his third straight defeat.
And Roach, a former boxer who suffers from Parkinson's disease, said they had an "agreement" that Pacquiao would retire if advised to by his trainer.
He said if Pacquiao wins in Macau, they will seek a rematch with Marquez as a priority ahead of the long-awaited match-up with undefeated American Floyd Mayweather.
"We want Marquez one more time, yes. That's the fight we want," he said. "Mayweather too of course, but Marquez, he got lucky and we want to take that back."
Pacquiao wraps up his training camp and departs for Macau on Monday, ahead of the fight which will be held next Sunday morning local time so as to be live for Saturday evening TV audiences in the United States.