Pakistan captain Mohammad Hafeez won the toss and elected to bat against South Africa in the second Twenty20 international at SuperSport Park on Sunday.
Pakistan fielded a side featuring its first-choice 11 experienced players.
For South Africa fast bowler Kyle Abbott, who took man of the match in his debut test match against Pakistan last month with nine wickets, will also be making his Twenty20 international debut.
The first Twenty20 between the sides at Durban was washed out on Friday so the winner of Sunday's match will also clinch the series.
South Africa beat Pakistan 3-0 in the test series.
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